Stimulife Health

Place all ads Free!
HomeFAQRegisterLog in
Social bookmarking
Social bookmarking digg  Social bookmarking reddit  Social bookmarking stumbleupon  Social bookmarking slashdot  Social bookmarking google  Social bookmarking blogmarks  Social bookmarking live      

Bookmark and share the address of Stimulife Health on your social bookmarking website


 Metastasis and Fucoidan Research

Go down 

Male Number of posts : 253
Age : 52
Location : Albert,Canada
Job/hobbies : Exercise, online stuff and Motorcycles.
Picture : Vitality For Life!
Points : 43141
Registration date : 2007-12-21

Metastasis and Fucoidan Research Empty
PostMetastasis and Fucoidan Research

Metastasis and Fucoidan Research has shown that fucoidan directly affects cancer cells, causing apoptosis (cell death) in addition to enhancing immune reactions to cancer.

Metastasis is the mechanism that cancers use to spread around the body. In order to metastasize, cancer cells need to evade immune surveillance, survive and invade a new tissue. Earlier research has suggested that fucoidan can inhibit metastasis of solid tumor's.

Cancer cells may use selectins to attach to endothelial surfaces prior to invading a new tissue space. A pivotal paper by Gassmann et al demonstrated that metastasis could be inhibited in part by selectin blockade with fucoidan in animal models. Fucoidan also alters the interaction of stromal derived factor (SDF1) with heparan sulphate on the cell surface, potentially blocking the traffic of metastasizing cells.

Furthermore, fucoidan inhibits the activity of enzymes that break down connective tissues, which is associated with metastasis. Other mechanisms by which fucoidan can block metastasis are now being uncovered. In another recent study, researchers looked at the effect of Undaria pinnatifida fucoidan on the highly metastatic mouse liver cancer (hepatocarcinoma) Hca-F cell line in vitro and in vivo.  

Fucoidan inhibited tumour metastasis in vivo and cancer cell growth, migration, invasion, and adhesion capabilities in vitro.  Several markers were affected, involving inactivation of the NF-κß pathway mediated by PI3K/Akt and ERK signalling pathways. As this research progresses, we can expect more findings to support a potential role for fucoidan to be developed and applied as an anti-metastatic agent.

Gassmann P, Kang ML, Mees ST, Haier J. In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell-endothelial cell interaction. BMC Cancer. 2010 Apr 30;10:177. doi: 10.1186/1471-2407-10-177. Wang P, Liu Z, Liu X, Teng H, Zhang C, Hou L, Zou X.Anti-metastasis effect of fucoidan from Undaria pinnatifida sporophylls in mouse hepatocarcinoma Hca-F cells. PLoS One. 2014 Aug 27;9(Cool:e106071.

Our Daily Dose - Organic Super Greens Contains Fucoidan & 100% of the RDA of Iodine your body needs!

Order it Here!

If you'd like to experience the many health benefits of our organic and natural products as a consumer, we invite you to visit our online store and enjoy our complete selection!

Here's a Retail Coupon that will save you 10% on your 1st Order.  Just enter in this code at the checkout page. Code: retail1403

To assist you further, we invite you to e-mail us at

You can review our entire product line at

To enroll into the business opportunity part of our program, simply visit  Follow the prompts and after enrolling, we'll contact you with training material and support - to build your new enterprise into whatever you dream of it becoming!

Whether you are a customer or a business affiliate - We know your future is much too important to trust just anyone!

To Your Health Success!

Regeneration USA

*Traffic -  2017. Free information: OTO Hits
Back to top Go down
Share this post on: diggdeliciousredditstumbleuponslashdotyahoogooglelive

Metastasis and Fucoidan Research :: Comments

No Comment.

Metastasis and Fucoidan Research

Back to top 

Page 1 of 1

Permissions in this forum:You cannot reply to topics in this forum
Stimulife Health :: Main Forum :: Working From Home Opportunities :: Health & Wellness-
Jump to: